TABLE 2.

Summary of the HDAC family analysis overall result significance p-value.

	HDAC1	HDAC2	HDAC3	HDAC4	HDAC5	HDAC6	HDAC7	HDAC8	HDAC9	HDAC10	HDAC11
Gene expression (glioma vs. control)
ONCOMINE	3.08e-08	2.70e-10	—	1.70e-13	6.80e-20	8.88e-13	—	—	—	—	3.14e-14
GEPIA (|Log2FC|>1)	<0.0100	<0.0100	>0.0100	>0.0100	>0.0100	>0.0100	>0.0100	>0.0100	>0.0100	>0.0100	(GBM) < 0.01
Clinical trait correlation
CGGA (WHO grade II - III - IV)	1.25e−13	0.0025	2.51e−09	4.79e−18	2.48e−12	0.3670	1.43e−19	3.48e−10	0.8700	0.7150	3.74e−12
CGGA (IDH1 mutation - IDH1 wildtype)	5.50e−16	0.0098	3.30e−05	8.80e−22	1.95e−15	0.1870	1.21e−28	0.0098	0.0526	0.9100	9.53e−05
CGGA (1p/19q codeletion - non-codeletion)	5.06e−57	0.6400	1.98e−10	1.17e−15	8.36e-04	0.0590	3.60e−16	0.1063	0.0202	0.5280	0.0580
Survival analysis (high-expression vs. low-expression)
GEPIA (Overall survival)	<0.0001	0.0240	<0.0001	<0.0001	<0.0001	0.0063	<0.0001	0.5500	0.0840	0.0610	2.10e−14
CGGA (Overall survival)	<0.0001	0.3900	0.01200	<0.0001	<0.0001	0.0012	<0.0001	0.0056	0.1100	0.2400	<0.0001
GEPIA (Disease Free survival)	<0.0001	0.1200	2.10e−15	1.10e−16	9.40e−12	0.01400	3.00e−09	0.9900	0.0026	0.0092	4.80e−08