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. Author manuscript; available in PMC: 2021 Sep 15.
Published in final edited form as: Indian J Rheumatol. 2021 Mar 23;16(1):57–72. doi: 10.4103/injr.injr_210_20

Table 2:

Comparison of adult rheumatoid arthritis microbiome studies

RA microbiome Study # samples Tissue (country) Lower abundance in RA patients versus HC Increased abundance in RA patients versus HC
RA (n=42)
HC (n=10)
Fecal (Italy)[23] 		Faecalibacterium, Flavobacterium, Blautia Lactobacillus
RA (n=40)
HC (n=32)
Fecal (USA)[7] 		Faecalibacterium Actinobacteria, Collinsella, Eggerthella, Actinomyces
NORA (n=44)
HC (n=28) (USA)[25] 		Bacteroides Prevotella copri
RA (n=77)
HC (n=80)
Fecal (China)[24] 		Haemophilus spp., Veillonella, Klebsiella pneumoniae, Bifidobacterium bifidum, Sutterella wadsworthensis, Megamonas hypermegale Lactobacillus, Eggerthella, Clostridium asparagiforme, Gordonibacter, Pamelaeae, Lachnospiraceae bacterium
RA (n=21)
HC (n=23)
Fecal (Canada)[22] 		Roseburia, Gemmiger, Lachnospira, Sporobacter Actinomyces, Eggerthella Clostridium III, Faecalis coccus Streptococcus
RA (n=110)
HC (n=155)
Oral (China)[5] 		Neisseria subflava, Haemophilus parainfluenzae, Veillonella dispar, Prevotella tannerae, Actinobacillus parahaemolyticus, Neisseria, Haemophilus, Prevotella, Veillonella, Fusobacterium, Aggregatibacter, Actinobacillus

RA: Rheumatoid Arthritis, HC: Healthy control