Table 3:
Comparison of adult Systemic lupus erythematosus microbiome studies
| SLE microbiome study # samples Tissue (country) | Lower abundance in SLE patients versus HC | Increased abundance in SLE patients versus HC |
|---|---|---|
| SLE (n=20) HC (n=20) Fecal (Spain)[26] |
Firmicutes | Bacteroidetes |
| SLE (n=45) Fecal (China)[27] |
Dialister, Pseudobutyrivibrio | Rhodococcus, Eggerthella, Klebsiella, Prevotella, Eubacterium, Flavonifractor |
| SLE (n=14) Non-SLE control (n=17) Fecal (USA)[28] |
Odoribacter | Proteobacteria, Blautia |
| SLE (n=61) Fecal (USA)[29] |
Ruminococcus gnavus | |
| SLE (n=52) HC (n=52) Oral (Brazil)[30] |
Fretibacterium, Prevotella nigrescens, Selenomonas | |
| SLE (n=20) HC (n=19) Oral (China)[31] |
Sphingomonadaceae, Halomonadaceae, Xanthomonadaceae | Lactobacillaceae, Veillonellaceae, Moraxellaceae |
SLE: Systemic lupus erythematosus, HC: Healthy control