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. Author manuscript; available in PMC: 2021 Sep 15.
Published in final edited form as: Psychiatr Clin North Am. 2011 Jun;34(2):335–iii. doi: 10.1016/j.psc.2011.02.005

Fig. 2.

Fig. 2.

Hierarchy of predictors of treatment response with an aggressive treatment approach. Main outcome, full response status at week 12; proportion of responders at 12 weeks, 60%. A change in HRSD score at week 4 of less than 45% from baseline predicts a less-than-half (43%) chance of responding at week 12. For the patients in this group, higher baseline anxiety predicts a 39% chance of responding at week 12. For patients with a higher baseline anxiety, a younger age of onset predicts a 32% chance of responding at week 12. (From Andreescu C, Mulsant BH, Houck PR, et al. Empirically derived decision trees for the treatment of late-life depression. Am J Psychiatry 2008;165:859; with permission.)