Table 3.

T1 and T2 mapping values in comparison to reference ranges and also dichotomized based on those with and without MACE. Data are presented a z-scores and for specific MRI magnets and field strength

	ICI myocarditis patients	Reference Ranges	p*	MACE	No MACE	p†
T1 z-score (n=86)	2.9 ± 1.9	-	-	4.2 ± 1.0	2.3 ± 1.9	<0.001
T1 value - 1.5T Siemens (n=67)	1079.0±55.5	1000.3±22.1	<0.001	1114.7±40.9	1061.6±53.6	<0.001
T1 value - 1.5T Philips (n=4)	1014.0±34.0	961.5±23.0	0.007	1013 ± 0	1014.3 ± 41.6	N/A‡
T1 value - 3.0T Siemens (n=15)	1239.3±72.1	1097.3±144.6	<0.001	1244.0±64.0	1237.5±77.7	0.88
T2 z-score (n=79)	2.2 ± 2.1	-	-	3.2 ± 2.4	1.8 ± 1.7	0.003
T2 value - 1.5T Siemens (n=67)	56.2±4.9	49.8±2.2	<0.001	57.9±6.5	55.4±3.7	0.045
T2 value - 1.5T Philips (n=4)	55.0±4.1	51.9±0.6	0.28	54.0±0	55.3 ± 4.9	N/A‡
T2 value - 3.0T Siemens (n=8)	42.9±4.6	39.3±0.1	0.063	46.0±0	42.4±4.8	N/A‡

^*Student’s t-test comparing T1 or T2 values of patients with immune checkpoint inhibitor associated myocarditis with site- and magnet-specific normal mean values and standard deviation.

^†Student’s t-test comparing T1 or T2 values of patients with and without major adverse cardiovascular events.

^‡analysis could not be performed due only one patient in the MACE group.