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. Author manuscript; available in PMC: 2021 Sep 15.
Published in final edited form as: Clin Cancer Res. 2020 Nov 20;27(5):1371–1380. doi: 10.1158/1078-0432.CCR-20-3084

Table 3.

Association between continuous ERVs and clinical endpoints.

ERV Marker Nivo (OR/HR, p-value) Evero (HR, p-value)a
n ORR DRR PFS OS n PFS OS
ERVE4 n = 105 2.40, 0.119 4.05, 0.042 0.42, 0.020 0.70, 0.203 n = 104 1.24, 0.763 1.13, 0.635
hERV4700ENV n = 82 1.28, 0.310 1.48, 0.237 0.79, 0.194 0.59, 0.050 n = 80 0.78, 0.196 0.96, 0.445
a

Association of the biomarkers with ORR and DRR was not assessed in the evero arm due to the low number of responders.

Abbreviations: OR, odds ratio; HR, hazard ratio.