Table 2. Outcomes of CABG stratified by sex and multivariable regression analysis showing odds of developing post-operative complications following CABG in female patients with males as reference.
Variable | Female (%) | Male (%) | p-value | Unadjusted analysis | Adjusted analysisa | ||
---|---|---|---|---|---|---|---|
OR | p-value | OR | p-valueb | ||||
Stroke | 46 (3.2) | 54 (1.1) | <0.001 | ||||
Sepsis | 10 (0.7) | 24 (0.5) | 0.288 | ||||
DSMI | 14 (1.0) | 12 (0.2) | <0.001 | ||||
Ventilator dependence >48 hours | 200 (13.9) | 398 (7.8) | <0.001 | 1.92 (1.60, 2.30) | <0.001 | 1.65 (1.21, 2.45) | 0.002 |
Pneumonia | 26 (1.8) | 97 (1.9) | 0.837 | ||||
Renal Failure | 49 (3.4) | 81 (1.6) | <0.001 | 2.20 (1.53, 3.15) | <0.001 | 0.99 (0.63, 1.54) | 0.946 |
Heart Block | 21 (1.5) | 26 (0.5) | <0.001 | ||||
Cardiac Arrest | 26 (1.8) | 55 (1.1) | 0.026 | ||||
GI complications | 29 (2.0) | 88 (1.7) | 0.446 | 1.18 (0.77, 1.80) | 0.447 | 0.94 (0.59, 1.49) | 0.788 |
Atrial Fibrillation | 338 (23.6) | 1269 (24.8) | 0.333 | 0.93 (0.81, 1.07) | 0.333 | 1.10 (0.96, 1.26) | 0.202 |
Reoperation for cardiac complication | 17 (1.2) | 32 (0.6) | 0.030 | ||||
Reoperation for non-cardiac complication | 66 (4.9) | 191 (3.9) | 0.094 | 1.37 (0.95, 1.98) | 0.095 | 1.24 (0.23, 1.86) | 0.293 |
Cardiac readmission | 140 (9.8) | 282 (5.5) | <0.001 | 1.85 (1.50, 2.29) | <0.001 | 1.56 (1.27, 2.30) | 0.003 |
Non-cardiac readmission | 161 (11.2) | 324 (6.3) | <0.001 | 1.87 (1.53, 2.28) | <0.001 | 1.16 (0.77, 2.40) | 0.402 |
Duration of stay (days) c | 7.19 ± 5.93 | 6.30 ± 4.64 | <0.001 | 0.074 (0.148) | <0.001 | -0.108 (0.182) | 0.554 |
30 day Mortality | 46 (3.2) | 75 (1.5) | <0.001 | 2.23 (1.54, 3.23) | <0.001 | 1.55 (1.01, 2.40) | 0.046 |
aAdjusted for, obesity, smoking status, diabetes, hypertension, history of myocardial infarction, heart failure, pre-operative ejection fraction and IABP use, heparin and anti-platelets, number of diseased vessels, IMA utilization, number of arterial and venous grafts and year of surgery.
bBonferroni correction applied for multivariable regression—p<0.0045 considered significant.
cResults of Linear regression analysis reported as standardized coefficient (coefficient standardized error)
DSMI: Deep sternal mediastinal infection; GI: gastrointestinal; IMA: Internal mammary artery.