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. 2021 Feb 16;31(4):370–376. doi: 10.4103/ijn.IJN_289_20

Table 1.

Clinical characteristics of the recipients and the donors

Characteristics Group 1 (n=150) n (%) Group 2 (n=1000) n (%) P
Age, years ± (SD) 69±7.5 41±8 0.02
Male gender, n (%) 120 (80) 820 (82) -
ESRD cause, n (%)
 Diabetes mellitus 79 (52.3) 414 (41.4) NS
 Chronic Glomerulonephritis 30 (20.33) 300 (30) -
 Chronic interstitial nephritis 22 (14.7) 228 (22.8) -
 Hypertensive nephrosclerosis 12 (8.33%) 10 (1) <0.05
 Undetermined 7 (4.37) 48 (4.8) -
Co-morbidities
 Diabetes 82 (55) 452 (45.2) NS
 Hypertension 127 (85) 900 (90) -
 Coronary artery disease 46 (31) 250 (25) -
 Peripheral artery disease 9 (6) 30 (3) -
 Chronic obstructive pulmonary disease 12 (8) 40 (4) -
 ABO-incompatible 25 (17) 250 (25) NS
 Pre-emptive Transplant 20 (13.5) 160 (16) -
 Median time in dialysis, months 12 (2-36) 8 (1-30) NS
 Hemodialysis 115 (88) 750 (89.2) -
 Peritoneal dialysis 15 (12) 90 (10.7) -
HLA Mismatch
 1 25 (16.7) 208 (20.8) -
 2 23 (15.7) 170 (17) -
 3 31 (20.7) 180 (18) -
 4 21 (14.7) 140 (14) -
 5 32 (22.0) 172 (17.2) -
 6 19 (13.3) 130 (13) -
Donor characteristics
Age
 < 50 years 57 (38) 790 (79) <0.05
 50-60 years 69 (45.8) 200 (20) 0.02
 60-70 years 24 (16.2) 10 (1) 0.004
 Living donors (%) 150 (100) 1000 (100) -
Relationship with recipient, n (%)
 Siblings 56 (37.5) 144 (14.4) <0.05
 Spouse 54 (35.5) 390 (39) NS
 Children 3 (2) 3 (0.3) -
 Other relatives 37 (25) 131 (13.1) -
 Parents - 332 (33.2) 0.002
 Induction agent 123 (82) 840 (84) -
 Basiliximab 34 (27.8) 200 (23.8) -
 Anti- thymocyte globulin 89 (72.2) 640 (76.2) -
Initial immunosuppression
 Steroid +Mycophenolate Mofetil + tacrolimus 142 (95.2) 978 (97.8) NS
 Steroid + Mycophenolate Mofetil + Cyclosporine 6 (3.4) 12 (1.2) NS
 Steroid + Azathioprine + Tacrolimus 2 (1.4) 10 (1) NS