Table 6.

Relative Risks for Progression to Advanced Age-Related Macular Degeneration According to Intake of Nuts

	No. of Servings of Nuts per Week			P Value (Trend)
	Never	<1	≥1
Nuts*
Sample size	136	66	59	…
Median intake	0	0.08	0.14	…
Adjusted RR†	1.0	0.74	0.46	.008
Multivariate RR 1 (95% CI)‡	1.0	0.66 (0.39–1.10)	0.54 (0.29–1.01)	.02
Multivariate RR 2 (95% CI)§	1.0	0.69 (0.40–1.17)	0.60 (0.32–1.02)	.05

Abbreviations: CI, confidence interval; RR, relative risk.

^*Nuts refers to servings per day of any type of nut.

^†Adjusted for age-sex group (men aged 60–69 years, men aged 70–79 years, men aged ≥80 years, women aged 60–69 years, women aged 70–79 years, and women aged ≥80 years), log energy (continuous), and protein intake (quartile).

^‡Adjusted for age-sex group (men aged 60–69 years, men aged 70–79 years, men aged ≥80 years, women aged 60–69 years, women aged 70–79 years, women aged ≥80 years), education (≥high school vs ˂high school), smoking (current, past, or never), body mass index (˂25, 25–29.9, and ≥30), systolic blood pressure, cardiovascular disease, log energy (continuous), protein intake (quartile), energy-adjusted log beta carotene intake (continuous), alcohol intake (continuous), physical activity (continuous, mean number of times per week of vigorous activity), and initial age-related macular degeneration grade (categorical).

^§Adjusted for variables in multivariate RR 1 plus total intake of energy-adjusted log zinc, vitamin C, and vitamin E.