Skip to main content
. Author manuscript; available in PMC: 2021 Dec 9.
Published in final edited form as: Neuron. 2020 Sep 30;108(5):953–967.e8. doi: 10.1016/j.neuron.2020.09.012

Figure 6. Stable Object Angle Preference Despite Active Ensemble Turnover after 2-Angle Discrimination Training.

Figure 6.

(A) Example FOV (same as Figure 3) of active ROIs from 7-angle test sessions before (left) and after (center) 2-angle training. (Right) Overlay with persistently active in white. (Bottom left) Magnified view of white dashes above. Scale bars: 100 μm (top), 50 μm (bottom).

(B) Classification flow of 11,351 active neurons in 6 mice from naive to expert 7-angle test session.

(C) Cumulative proportion of rate of inferred spikes from persistent (active in both sessions) or transient (active in only 1) neurons in naive or expert 7-angle test sessions. (Inset) Mean rate of inferred spikes with paired t tests.

(D) Proportion of active neurons that were angle tuned in naive and expert 7-angle test sessions. Paired t test.

(E) Normalized activity of all angle-tuned neurons from 6 expert mice in naive and expert 7-angle sessions, sorted by maximally preferred angles.

(F) Distribution of preferred angles in naive and expert mice.

(G) Distribution of change in preferred angles in persistently angle-tuned neurons across training (black bars). Gray bars: shuffled data.

Data are shown in means ± SEMs.

See also Figures S6 and S7.