. Author manuscript; available in PMC: 2022 Mar 1.

Published in final edited form as: Psychoneuroendocrinology. 2020 Dec 28;125:105123. doi: 10.1016/j.psyneuen.2020.105123

Table 3.

Summary of Multiple Regression Models

	AUCg			Highest

Variable	β	SE	p value	β	SE	p value

L Amygdala-vmPFC RSFC predicting TSST for MDD
L Amygdala-vmPFC RSFC	6.20	2.65	.02^*	.15	.05	.01^*
Diagnosis	1.92	2.65	.47	.02	.05	.78
L Amygdala-vmPFC × MDD	−7.80	3.37	.02^*	−.18	.07	.01^*
Adjusted R²		.04			.06

R amygdala-dmPFC RSFC predicting TSST for MDD
R amygdala-dmPFC RSFC	−1.71	3.55	.63	.01	.07	.85
Diagnosis	2.14	2.63	.42	.02	.05	.70
R amygdala-dmPFC × MDD	−7.21	4.83	.14	−.18	.10	.07
Adjusted R²		.06			.04

L amygdala-vmPFC RSFC predicting TSST for NSSI
L amygdala-vmPFC RSFC				.15	.05	.01^*
MDD/noNSSI				.05	.07	.43
MDD/NSSI				−.02	.06	.78
L amygdala-vmPFC × MDD/noNSSI				−.16	.08	.05
L amygdala-vmPFC × MDD/NSSI				−.22	.08	.01^*
Adjusted R²					.05

R amygdala-dmPFC RSFC predicting TSST for NSSI
R amygdala-dmPFC RSFC	−1.71	3.52	.63
MDD/noNSSI	3.59	3.23	.27
MDD/NSSI	.38	2.95	.90
R amygdala-dmPFC × MDD/noNSSI	−11.07	5.50	.05^*
R amygdala-dmPFC × MDD/NSSI	0.06	6.31	.99
Adjusted R²		.08

Note. MDD = major depressive disorder; NSSI = nonsuicidal self-injury; TSST = Trier Social Stress Test; AUCg = area under the curve with respect to ground; vmPFC = ventral medial prefrontal cortex; dmPFC = dorsal medial prefrontal cortex; RSFC = resting state functional connectivity; RSFC are z values centered at the mean. The reference group is the healthy control group.

indicates p < .05.