Table 2.

Treatment-emergent adverse events of ≥ grade 3 in study population

All patients, N=132 N (%)
Total number of grade ≥3 TEAEs occurring in ≥ 2 patients	56 (42.4)
Anemia	24 (18.2)
Thrombocytopenia	18 (13.6)
Lymphopenia	14 (10.6)
Diarrhea	12 (9.1)
Febrile neutropenia	10 (7.6)
Neutropenia	10 (7.6)
Hyponatremia	7 (5.3)
Leucopenia	6 (4.5)
Hypokalemia	5 (3.8)
Fatigue	2 (1.5)
Oral mucositis	2 (1.5)
Anorexia	2 (1.5)
Syncope	2 (1.5)
Renal disorders	2 (1.5)
Patients with any SAEs	19 (14.4)
SAEs occurring in ≥ 2 patients
Syncope	2 (1.5)
Febrile neutropenia	7 (5.3)
Colitis	4 (3.0)
Nausea	2 (1.5)
Neutropenia	3 (2.3)
Urinary tract infections	3 (2.3)
Diarrhea	3 (2.3)
Acute kidney injury	2 (1.5)