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Proposed pathways involved in neuroprotective and anti-inflammatory activities of Emblica officinalis. (a) EO crude fruit extract significantly attenuated proinflammatory cytokine IL-6, NO, and TNF-α in LPS-induced BV2 cells via the ERK1/2 and JNK signaling pathways. (b) Neuroprotective effects are associated with enhanced neurite outgrowth that the TuJ1 and MAP2 mRNA expressions may influence.
