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. 2021 Sep 7;2021:6632813. doi: 10.1155/2021/6632813

Figure 7.

Figure 7

rhGPx4 inhibits cardiomyocyte apoptosis in the heart tissue. (a) Representative images of TUNEL staining of the heart tissue (optical microscope, ×400). The apoptotic cardiomyocyte nucleus appears brown, and normal nuclei appear blue. (b) Ratio of TUNEL-positive cells (%). (c) Representative western blot bands of Bcl-2, Bax, Cleaved caspase-3, and β-actin. (d) The ratio of the Bcl-2/Bax expression in the heart tissue. (e) The expression levels of cleaved caspase-3 in the heart tissue. Data represent the mean ± SD (n = 3). ##P < 0.01, ###P < 0.001 vs. control; ∗∗P < 0.01 vs. ISO.