Table 2.
The association of inflammatory indexes with clinical characteristics in patients with stage IIB cervical cancer.
| Clinical characteristics | N | PLRa | NLRa | MLRa | BLRa | SIRIa |
|---|---|---|---|---|---|---|
| Age | ||||||
| ≤51 years | 139 | 173.87 (132.56, 215.35) | 2.90 (2.11, 3.95) | 0.29 (0.21, 0.37) | 0.022 (0.014, 0.033) | 1.22 (0.72, 1.93) |
| >51 years | 121 | 126.25 (97.70, 172.36) | 2.10 (1.63, 2.80) | 0.23 (0.17, 0.32) | 0.021 (0.015, 0.029) | 0.84 (0.55, 1.25) |
| P value | <0.001 | <0.001 | 0.001 | 0.399 | <0.001 | |
| Menopause | ||||||
| Yes | 137 | 126.37 (99.80, 174.56) | 2.11 (1.65, 2.80) | 0.23 (0.17, 0.32) | 0.021 (0.015, 0.030) | 0.81 (0.55, 1.30) |
| No | 123 | 176.79 (137.91, 218.57) | 3.06 (2.14, 4.12) | 0.29 (0.22, 0.39) | 0.022 (0.015, 0.031) | 1.22 (0.77, 2.11) |
| P value | <0.001 | <0.001 | <0.001 | 0.532 | <0.001 | |
| Pathologyb | ||||||
| SCC | 245 | 154.17 (113.58, 205.16) | 2.55 (1.92, 3.54) | 0.26 (0.19, 0.35) | 0.021 (0.015, 0.030) | 1.04 (0.64, 1.61) |
| Adenocarcinoma | 14 | 159.84 (96.14, 198.12) | 1.90 (1.40, 2.75) | 0.22 (0.16, 0.29) | 0.029 (0.019, 0.034) | 0.73 (0.32, 1.33) |
| P value | 0.875 | 0.026 | 0.098 | 0.120 | 0.072 | |
| Tumor size | ||||||
| <4 cm | 78 | 124.22 (95.54, 169.07) | 2.08 (1.51, 2.74) | 0.23 (0.17, 0.30) | 0.022 (0.014, 0.030) | 0.77 (0.55, 1.22) |
| ≥4 cm | 182 | 167.17 (124.07, 215.05) | 2.75 (2.05, 3.80) | 0.27 (0.20, 0.36) | 0.021 (0.015, 0.031) | 1.16 (0.71, 1.78) |
| P value | <0.001 | <0.001 | 0.013 | 0.736 | <0.001 | |
| Lymphatic metastasis | ||||||
| Yes | 61 | 182.21 (127.89, 218.90) | 2.95 (2.16, 4.05) | 0.30 (0.24, 0.40) | 0.021 (0.015, 0.033) | 1.35 (0.90, 2.23) |
| No | 196 | 152.26 (108.01, 193.80) | 2.32 (1.76, 3.17) | 0.24 (0.17, 0.32) | 0.022 (0.015, 0.030) | 0.93 (0.58, 1.39) |
| P value | 0.011 | 0.001 | <0.001 | 0.655 | <0.001 | |
| Neoadjuvant chemotherapy | ||||||
| Yes | 243 | 155.10 (115.83, 203.14) | 2.56 (1.91, 3.49) | 0.26 (0.19, 0.35) | 0.021 (0.015, 0.030) | 1.06 (0.64, 1.59) |
| No | 17 | 125.00 (97.61, 205.16) | 2.09 (1.43, 2.84) | 0.23 (0.16, 0.31) | 0.020 (0.013, 0.034) | 0.73 (0.47, 1.12) |
| P value | 0.271 | 0.178 | 0.350 | 0.763 | 0.039 |
PLR, platelet-to-lymphocyte ratio; NLR, neutrophil-to-lymphocyte ratio; MLR, monocyte-to-lymphocyte ratio; BLR, basophil-to-lymphocyte ratio; SIRI, systemic inflammation response index; SCC, squamous cell carcinoma. aThe values of PLR, NLR, MLR, BLR, and SIRI were all expressed as median (first quartile, third quartile). bSCC (squamous cell carcinoma) consists of PDSCC (poorly differentiated squamous cell carcinoma), MDSCC (moderately differentiated squamous cell carcinoma), and WDSCC (well differentiated squamous cell carcinoma). Adenocarcinoma includes adenocarcinoma and adenosquamous carcinoma.