Table 3.
Summary of extracted data
| Author | Study type (POS, ROS, RCT) |
Number of pt | Age (years) | Gender | Mean radia tion dosage (gray) |
HBO | Impl location (number of impl) |
Impl placed | Mean time interval | Impl in situ |
Impl lost | ORN cases | Mean follow-up (msonths) |
|||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Male | Female | max vs. mand | Native vs. graft | RT and impl (months) | Impl and loading (months) | |||||||||||
| Bodard et al. 2006 [93] | ROS | 33 | 60.3 | 32 | 1 | 60.5 | 0 |
max: 6 mand: 62 |
Native | 68 | 54.2, Post-RT | 7 | 68 | 0 | 0 | 31.9 |
| Landes et al. 2006 [47] | ROS | 30 (total) | 63 | 22 | 8 | Ø | Ø | mand | Native | 114 | Ø | 25 days | 113 | 1 | 0 | 36 |
| 11 | Ø | Ø | 0 | Ø | mand | Native | 42 | Ø | 25 days | 42 | 0 | 0 | Ø | |||
| 19 | Ø | Ø | 57 | Ø | mand | Native | 72 | 21, Post-RT | 25 days | 71 | 1 | 0 | Ø | |||
| Schoen PJ et al. 2007 [94] | RCT | 13 | 61.2 | 8 | 5 | 64.5 | 0 | mand | Native | 49 | 48, Post-RT | 6 | 46 | 3 | 0 | Ø |
| 13 | 57.7 | 9 | 4 | 60.5 | 13 | mand | Native | 54 | 45, Post-RT | 6 | 46 | 8 | 1 | Ø | ||
| Liberali 2009 [95] |
POS (Non-RCT) |
14 | 59.6 | 13 | 1 | 61.57 | 14 | mand | Ø | 28 | 67.7, post-RT | 6.5 | 25 | 3 |
1 (+ 1 after implant failure) (+ 1 unrelated to implant site) |
Ø |
| Fenlon et al. 2012 [59] | ROS | 29 | Ø | Ø | 0 | Ø | mand | Graft | 110 | Ø | Ø | 107 | 3 | 0 | Ø | |
| 12 | Ø | Ø | 65 | Ø | mand | Graft | 35 | Pre-RT | 6 | 20 | 15 | 3 | Ø | |||
| Linsen et al. 2012 [96] | ROS | 66 | 55.7 | 43 | 23 | Ø | 0 |
max: 49 mand: 213 |
Native: 183 graft: 79 |
262 | 41, post-RT | 4.9 | 248 | 14 | 0 | 47.99 |
| 32 | Ø | Ø | 0 | 0 |
max: 36 mand: 103 |
native: 95 graft: 44 |
139 | Ø | 4.9 | 133 | 6 | 0 | Ø | |||
| 34 | Ø | Ø |
60: 8 pt 36: 26 pt |
0 |
max: 13 mand: 110 |
native: 42 graft: 81 |
123 | 41, post-RT | 4.9 | 115 | 8 | 0 | Ø | |||
| Curi et al. 2018 [97] | ROS | 35 | 65 | 18 | 17 | 62 | 13 |
max: 79 mand: 90 |
Ø | 169 | 23.7, post-RT | 6 | 157 | 12 | 0 | 89.2 |
| Desoutter et al. 2018 [98] | ROS | 18 | 57.5 | 14 | 4 | 51.8 | Ø | mand | native | 40 | 44.6, post-RT | 2–4 | 32 | 8 | (+ 1 after implant failure) | Ø |
| Takahashi et al. 2018 [99] | ROS | 23 (total) | 71.4 | 11 | 12 | Ø | Ø |
max: 54 mand: 49 |
native: 80 graft: 23 |
103 | Ø | 91 | 12 | 0 | 64.4 | |
| 6 | Ø | Ø | 59 | Ø | Ø | 11 | Ø | 5 | 6 | 0 | Ø | |||||
HBO, hyperbaric oxygen therapy; impl, implants; mand., mandible; max, maxilla; ORN, osteoradionecrosis; POS, prospective observational study; pt, patients; RCT, randomized control study; ROS, retrospective observational study; RT, radiotherapy; Ø, unspecified