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. 2021 Sep 15;11:18322. doi: 10.1038/s41598-021-97834-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(A-D) Overtime changes in apical and global circumferential strains. (A) Endocardial apical circumferential strain (ACS); (B) Epicardial apical circumferential strain (ACS); (C) Endocardial global circumferential strain (GCS); (D) Epicardial global circumferential strain (GCS). The two data points at the chronic time point with a red cross (in endocardial ACS and GCS) represent outliers greater than the third quartile plus 1.5 times the interquartile range. (E–G): Overtime changes in LVEF, endocardial and epicardial ACS rates. (E) Left Ventricular Ejection Fraction (LVEF); (F) Endocardial apical circumferential strain (ACS) rates; (G) Epicardial ACS rates. The asterisk denotes changes considered significant with p < 0.0024. Statistical test: Mann–Whitney (* = identifies significant difference)”.