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. 2021 Sep 15;11:18710. doi: 10.1038/s41598-021-98196-1

Table 3.

Logistic regression analysis according to Raynaud scan results.

Variables Univariate analysis Multivariate analysisa
Crude OR (95% CI) p value Adjusted OR (95% CI) p value
Demographics
Age (years) 0.951 (0.909–0.994) 0.026
Sex 0.724 (0.255–2.057) 0.544
Associated symptoms
Affected limb edema 6.603 (1.677–26.005) 0.007 15.364 (2.774–85.087) 0.002
Abnormal sensation 0.823 (0.275–2.465) 0.728
Conventional risk factors (%)
Hypertension 0.515 (0.196–1.354) 0.179
Diabetes mellitus 0.655 (0.244–1.758) 0.401
Dyslipidemia 0.831 (0.288–2.392) 0.731
Atrial fibrillation 3.310 (0.619–17.715) 0.162
Smoking 3.500 (1.157–10.589) 0.027
Previous stroke 0.643 (0.182–2.266) 0.492
Neurological Severity
Proximal muscle strength 0.798 (0.478–1.330) 0.386
Distal muscle strength 0.978 (0.622–1.537) 0.923
Stenosis of artery
Intracranial 1.375 (0.521–3.631) 0.520
Extracranial 1.383 (0.424–4.514) 0.591
Distribution of ischemic lesion
Anterior circulation 4.200 (1.307–13.497) 0.016 4.540 (1.257–16.397) 0.021
Cortex 3.026 (0.932–9.829) 0.065 4.885 (0.893–26.723) 0.067
Laboratory findings
White blood cell (103/µl) 1.082 (0.894–1.309) 0.419
Hemoglobin (1003/µl) 1.004 (0.777–1.296) 0.978
Platelet (103/µl) 1.001 (0.994–1.008) 0.771
ESR (mm/hr) 1.015 (0.976–1.056) 0.451
hs-CRP (mg/L) 0.989 (0.944–1.035) 0.630
Total cholesterol (mg/dl) 1.002 (0.987–1.016) 0.830
Triglycerides (mg/dl) 1.000 (0.995–1.005) 0.947
HDL (mg/dl) 1.023 (0.978–1.071) 0.325
LDL (mg/dl) 0.998 (0.984–1.012) 0.774
HbA1c (%) 1.036 (0.748–1.435) 0.830

OR odds ratio, CI confidence interval, ESR erythrocyte sedimentation rate, hs-CRP high sensitivity C-reactive protein, HDL high density lipoprotein, LDL low density lipoprotein, HbA1c hemoglobin A1c.

aAdjusted for age, smoking, affected limb edema, anterior circulation, and cortex.