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. 2021 Sep 2;12:697643. doi: 10.3389/fphar.2021.697643

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Copyright © 2021 Chen, Han, Shi, Liu and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Melatonin relieves inflammation in CLP-induced mice. Kidney tissue inflammatory cytokine Il-1α (A), Il-1β (B), Mcp-1 (C), and Tgf-β1 (D) mRNA levels are measured using RT-PCR (* vs. sham, p < 0.05; # vs. CLP, p < 0.05).