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Potential protective mechanism of melatonin on AKI. A diagrammatic representation of some of the protective mechanism of melatonin on AKI. Abbreviations: Sirt3, Sirtuin-3; TGF-β1, transforming growth factor-β1; RIPK, receptor-interacting protein kinase; NF-κB, nuclear factor kappa-B; ROS, reactive oxygen species; AKI, acute kidney injury.
