Skip to main content
. 2021 Sep 14;3(9):e0527. doi: 10.1097/CCE.0000000000000527

TABLE 1.

Characteristics of 993 Patients From the Medical, Surgical, and Cardiovascular ICU With Serum Albumin Measured Within 1 Day of Enrollment

Characteristics No ARDS (n = 731) ARDS (n = 262) Overall (n = 993) p
Age, yr, median (IQR) 56 (45–67) 56 (47–65) 56 (47–56) 0.868
Male sex, n (%) 394 (54) 135 (52) 529 (53) 0.517
Albumin, g/dL, median (IQR) 2.7 (2.3–3.2) 2.5 (2.2–3.0) 2.8 (2.3–3.1) < 0.001
ICU location, n (%)
 Surgical 79 (11) 33 (13) 112 (11) 0.053
 Medical 622 (85) 226 (86) 848 (85)
 Cardiovascular 30 (4) 3 (1) 33 (3)
Risk factors for ARDS at enrollment, n (%)
 Nonpulmonary sepsis 283 (39) 108 (41) 391 (39) < 0.001
 Pneumonia 98 (13) 78 (30) 176 (18)
 Multiple transfusions 93 (13) 11 (4) 104 (10)
 Aspiration 44 (6) 48 (18) 92 (9)
 Pancreatitis 20 (3) 2 (1) 22 (2)
 Drug overdose 32 (4) 1 (0) 33 (3)
 Other 8 (1) 11 (4) 19 (2)
 None 116 (16) 2 (1) 118 (12)
 Not available/missing 37 (5) 1 (0) 38 (4)
Acute Physiology and Chronic Health Evaluation  Score II score, median (IQR) 26 (21–32) 30 (25–36) 27 (22–33) < 0.001
72-hr cumulative fluid balance liters, median (IQR) +3.0 (0.0–6.1) +4.1 (1.2–7.7) +3.2 (0.5–6.6) 0.001
Inhospital AKI by Kidney Disease Improving Global Outcomes stage, n (%)
 No AKI (stage 0) 138 (19) 24 (9) 162 (16) < 0.001
 AKI present (stages 1–3) 584 (80) 235 (89) 819 (82)
 Insufficient data 9 (1) 3 (1) 12 (1)
Baseline estimated glomerular filtration rate,  mL/min/1.73 m2, median (IQR) 75 (45–103) 82 (55–108) 77 (48–105) 0.013
Inhospital death, n (%) 163 (22) 107 (42) 270 (27) < 0.001
Days in ICU, median (IQR) 5 (3–9) 8 (5–13) 5 (3–10) < 0.001
Days on ventilator, median (IQR) 2 (0–5) 5 (3–9) 3 (0–6) < 0.001
Ventilator-free days, median (IQR) 25 (11–28) 13 (0–23) 23 (5–27) < 0.001

AKI = acute kidney injury, ARDS = acute respiratory distress syndrome, IQR = interquartile range.

p values compare ARDS with non-ARDS group with Fisher exact test for categorical variables and Mann-Whitney U test for continuous variables. Bold font indicates significant p values (p < 0.05).