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. 2021 Sep 16;12(1):73–89. doi: 10.1016/j.jtcme.2021.09.002

Fig. 1.

Fig. 1

The structural superimposition between the ACE2-free and ACE2-bound structures of the SARS-CoV-2 spike protein. The RBD cores of the SARS-CoV-2 spike protein in the ACE2-free structure and the ACE2-bound structure are respectively shown in cyan and green, and their RBMs are respectively shown in orange and yellow. The ACE2 receptor is also shown in red. The major difference between the RBD of the ACE2-free spike protein and the RBD of the spike-ACE2 complex protein is shown within the blue ring.