Table. Data Set Characteristicsa.
| Characteristic | Set 1 | Set 2 | |||
|---|---|---|---|---|---|
| Topcon (3D OCT-2000) | Topcon (3D OCT-2000) | Heidelberg (Spectralis OCT) | |||
| Condition | Wet AMD | Wet AMD | DME | Wet AMD | DME |
| Features segmented | IRF, SRF, PEDb | IRF, SRF, SHRM, PED | IRF, SRF | IRF, SRF, SHRM, PED | IRF, SRF |
| Total No. of OCT volumes | 15 | 46 | 42 | 46 (19 with 49 B-scans, 27 with 25 B-scans) | 24 (7 with 49 B-scans, 17 with 25 B-scans) |
| Sex, % | |||||
| Female | 47 | 59 | 55 | 50 | 50 |
| Male | 53 | 41 | 45 | 50 | 50 |
| Age, mean (SD), y | 75 (10) | NC | NC | NC | NC |
| No. of OCT volumes | |||||
| First presentation (treatment-naive) | 15 | 16 | 14 | 20 | 10 |
| After first treatment | |||||
| 3 mo | 0 | 15 | 15 | 14 | 8 |
| 12 mo | 0 | 15 | 13 | 12 | 6 |
| Total No. of B-scans | |||||
| Requiring assessment, mean (SD) | 1920 (128) | 5888 (128) | 5376 (128) | 1606 (35) | 768 (32) |
| With features manually segmented, counting both graders (mean [SD] per grader volume) | 3002 (100 [24]) | 6062 (66 [23]) | 5350 (64 [29]) | 2133 (23 [13]) | 880 (18 [13]) |
| Mean time taken per grader to manually segment a volume, h | 50 | 7c | |||
Abbreviations: AMD, age-related macular degeneration; DME, diabetic macular edema; IRF, intraretinal fluid; NC, not collected; OCT, optical coherence tomography; PED, pigment epithelial detachment; SHRM, subretinal hyperreflective material; SRF, subretinal fluid.
a
Scans were obtained using the 3D OCT-2000 device from Topcon Corporation (Topcon) and the Spectralis device from Heidelberg Engineering GmbH (Heidelberg) for wet AMD and DME.
b
Graders were asked to segment PED in 13 of 15 volumes in this pilot set of scans.
c
Mean time for the entirety of set 2.