Table 4.
Significant Factors of Survival in the Univariate and Multivariate Analyses
| Variable | Univariate | Multivariate | |||
|---|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | ||
| Age | 1.04 (0.99–1.09) | 0.093 | 0.083 | ||
| Male sex | 22.40 (0.06–8,171.43) | 0.302 | |||
| Smoking | 3.35 (0.8–13.98) | 0.098 | 3.31 (0.78–14.08) | 0.105 | |
| Alcohol consumption | 2.54 (0.61–10.6) | 0.201 | |||
| Charlson comorbidity index | 1.58 (1.29–1.93) | <0.001 | 1.61 (1.30–2.01) | <0.001 | |
| Tumor size | 1.06 (0.84–1.34) | 0.624 | |||
| Location | |||||
| Upper, mid third | 1 | ||||
| Lower third | 1.1 (0.57–2.18) | 0.762 | |||
| Depth of invasion | |||||
| m1, m2 | 1 | ||||
| m3 | 0.98 (0.38–2.54) | 0.965 | |||
| Tumor shape | |||||
| Flat | 1 | ||||
| Non-flat | 1.76 (0.87–3.56) | 0.115 | |||
| Differentiation | |||||
| Well, moderately- | 1 | 1 | |||
| Poorly- | 3.68 (0.85–15.83) | 0.085 | 2.28 (0.47–11.16) | 0.307 | |
| Multiplicity of lesion | |||||
| Solitary | 1 | ||||
| Multiple | 1.61 (0.49–5.28) | 0.429 | |||
| Lymphovascular invasion | |||||
| Absent | 1 | ||||
| Present | NA | 0.67 | |||
| Resection methods | |||||
| Endoscopic | 1 | 1 | |||
| Surgical | 1.19 (0.57–2.52) | 0.636 | 1.68 (0.71–3.98) | 0.238 | |
HR, hazard ratio; CI, confidence interval; m1, intraepithelial; m2, lamina propria; m3, muscularis mucosae; NA, not applicable.