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. 2021 Sep 16;84(2):248–288. doi: 10.1016/j.jinf.2021.09.005

Table 2.

Evaluation of factors associated with hyposmia/anosmia and dysgeusia in 423 healthcare workers with COVID-19 (Hospital das Clínicas, São Paulo, Brazil. January 22 - May 15, 2021).

Hyposmia/anosmia
Dysgeusia
Bivariate analysis
Multivariate analysis
Bivariate analysis
Multivariate analysis
OR(95%CI)a p Adj pb OR(95%CI)a p Adj pb OR(95%CI)a p Adj pb OR(95%CIa p Adj pb
Gamma variant 0.433(0.270–0.693) < 0.001 < 0.001 0.303(0.176–0.522) < 0.001 < 0.001 0.384(0.244–0.605) < 0.001 < 0.001 0.385(0.221–0.672) 0.001 0.011
Previous COVID-19 1.630(0.606–4.381) 0.333 1.000 1.317(0.465–3.734) 0.604 1.000 1.626(0.586–4.507) 0.350 1.000 1.321(0.458–3.806) 0.607 1.000
Fully immunizedc 0.856(0.561–1.306) 0.470 1.000 1.657(0.989–2.779) 0.055 0.605 0.784(0.500–1.230) 0.290 1.000 1.334(0.779–2.286) 0.294 1.000
Duration of symptoms 1.084(0.990–1.186) 0.081 0.891 1.119(1.020–1.227) 0.017 0.187 1.097(1.000–1.204) 0.50 1.000 1.125(1.023–1.236) 0.015 0.165
Female 1.250(0.801–1.951) 0.326 1.000 0.802(0.503–1.279) 0.354 1.000 0.975(0.605–1.573) 0.918 1.000 1.071(0.652–1.759) 0.788 1.000
Age strata (years)
16–40 1 (ref) 1 (ref) 1 (ref) 1 (ref)
41–60 0.734(0.468–1.151) 0.178 1.000 0.639(0.397–1.026) 0.064 0.704 0.821(0.512–1.318) 0.414 1.000 0.730(0.446–1.196) 0.212 1.000
>60 0.416(0.137–1.261) 0.121 1.000 0.281(0.083–0.947) 0.041 0.451 0.559(0.184–1.702) 0.306 1.000 0.408(0.121–1.377) 0.149 1.000
a

Odds ratio (95% confidence interval).

b

Adjusted p-value for multiple comparisons (11 symptoms) according to Bonferroni's correction.

c

Recipients of two doses of a COVID-19 vaccine as of 14 days after the second dose.