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Change in 24-h systolic blood pressure after renal denervation. Three randomized, sham-controlled trials demonstrating that radiofrequency- (SPYRAL HTN OFF and SPYRAL HTN ON) [[41], [42], [43]] and ultrasound-based (RADIANCE-HTN) [43] renal denervation can significantly reduce systolic blood pressure. ∗ including the pilot trial, SBP: systolic blood pressure, 24-h SBP: 24-h systolic blood pressure.
