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. 2021 Sep 16;28(1):114–123. doi: 10.1016/j.cmi.2021.09.010

Table 1.

Death according to gender, age, CCIS and association with obesity, diabetes or hypertension in 134 209 inpatients positive for SARS-CoV-2

Patients, n Deaths, n (%) Univariate analysis (95% CI) Multivariate analysis adjusted on age and CCIS (95% CI)
Female 63 872 8226 (12.9) 1 (Ref.) 1 (Ref.)
Male
70 337
11 743 (16.7)
1.4 (1.3–1.4)
1.5 (1.4–1.5)

Patients, n
Deaths, n (%)
Univariate analysis (95% CI)
Multivariate analysis adjusted on sex and CCIS (95% CI)
Age 18–49 years 32 928 524 (1.6) 1 (Ref.) 1 (Ref.)
Age 50–65 years 33 328 2683 (8.0) 5.4 (4.9–6.0) 4.1 (3.7–4.5)
Age 66–79 years 32 554 6113 (18.8) 14.3 (13.1–15.7) 9.1 (8.3–10.0)
Age ≥80 years
35 399
10 649 (30.1)
26.6 (24.3–29.1)
17.0 (15.5–18.6)

Patients, % (n)
Deaths, % (n)
Univariate analysis (95% CI)
Multivariate analysis adjusted on age and sex (95% CI)
CCIS = 0 36.4 (48 788) 4.9 (2412) 1 (Ref.) 1 (Ref.)
CCIS = 1 16.7 (22 468) 13.3 (2985) 2.9 (2.8–3.1) 1.6 (1.5–1.7)
CCIS = 2 11.2 (15 088) 18.2 (2749) 4.3 (4.0–4.5) 2.0 (1.8–2.1)
CCIS = 3 8.8 (11 861) 20.8 (2462) 5.0 (4.7–5.3) 2.1 (1.9–2.2)
CCIS = 4 6.4 (8540) 24.1 (2058) 6.1 (5.7–6.5) 2.4 (2.2–2.5)
CCIS from 5 to 7 13.9 (18 643) 26.7 (4968) 7.0 (6.6–7.4) 3.0 (2.8–3.1)
CCIS from 8 to 12 5.9 (7882) 27.5 (2167) 7.3 (6.8–7.8) 3.2 (3.0–3.4)
CCIS >12
0.7 (939)
17.9 (168)
4.2 (3.5–5.0)
2.7 (2.2–3.2)

Patients, % (n)
Deaths, % (n)
Univariate analysis (95% CI)
Multivariate analysis adjusted on sex, age and CCIS (95% CI)
No obesity 76.1 (102 139) 14.8 (15 067) 1 (Ref.) 1 (Ref.)
Obesity (total) 23.9 (32 070) 15.2 (4902) 1.04 (1.01–1.08) 1.17 (1.13–1.22)
Prevalent obesity 67.9 (21 768) 17.7 (3856) 1.24 (1.20–1.29) 1.27 (1.22–1.33)
Incident obesity 32.1 (10 302) 10.2 (1046) 0.65 (0.61–0.70) 0.94 (0.88–1.01)
No diabetes 76.0 (100 200) 13.3 (13 523) 1 (Ref.) 1 (Ref.)
Diabetes (total) 24.0 (32 209) 20.0 (6446) 1.64 (1.58–1.69) 1.16 (1.12–1.20)
Prevalent diabetes 71.5 (23 040) 22.4 (5166) 1.89 (1.82–1.96) 1.22 (1.17–1.27)
Incident diabetes 28.5 (9169) 14.0 (1280) 1.06 (1.00–1.13) 1.00 (0.94–1.07)
No hypertension 50.6 (67 596) 8.6 (5799) 1 (Ref.) 1 (Ref.)
Hypertension (total) 49.4 (66 613) 21.3 (14 170) 2.88 (2.79–2.98) 0.97 (0.94–1.01)
Prevalent hypertension 73.5 (48 932) 23.5 (11 500) 3.27 (3.16–3.39) 0.99 (0.96–1.04)
Incident hypertension 26.5 (17 681) 15.1 (2670) 1.90 (1.80–1.99) 0.92 (0.87–0.97)

Abbreviation: CCIS, Charlson's co-morbidity index score.