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. 2021 Sep 16;28(1):114–123. doi: 10.1016/j.cmi.2021.09.010

Table 2.

Invasive mechanical ventilation according to gender, age, CCIS and association with obesity, diabetes or hypertension

Patients, n Invasive mechanical ventilation, n (%) Univariate analysis (95% CI) Multivariate analysis adjusted on age and CCIS (95% CI)
Female 63 872 3883 (6.1) 1 (Ref.) 1 (Ref.)
Male
70 337
9713 (13.8)
2.5 (2.4–2.6)
2.0 (1.5–2.1)

Patients, n
Invasive mechanical ventilation, n (%)
Univariate analysis (95% CI)
Multivariate analysis adjusted on sex and CCIS (95% CI)
Age ≥80 years 35 399 931 (2.6) 1 (Ref.) 1 (Ref.)
Age 66 to 79 years 32 554 5257 (16.2) 7.1 (6.6–7.7) 6.8 (6.3–7.3)
Age 50 to 65 years 33 328 5461 (16.4) 7.3 (6.8–7.8) 7.8 (7.2–8.4)
Age 18 to 49 years
32 928
1947 (5.9)
2.3 (2.1–2.5)
3.2 (2.9–3.4)

Patients, % (n)
Invasive mechanical ventilation, % (n)
Univariate analysis (95% CI)
Multivariate analysis adjusted on age and sex (95% CI)
CCIS = 0 36.4 (48 788) 7.2 (3495) 1 (Ref.) 1 (Ref.)
CCIS = 1 16.7 (22 468) 11.6 (2596) 1.7 (1.6–1.8) 1.7 (1.6–1.8)
CCIS = 2 11.2 (15 088) 13.1 (1982) 2.0 (1.8–2.1) 2.1 (2.0–2.2)
CCIS = 3 8.8 (11 861) 12.6 (1496) 1.9 (1.7–2.0) 2.1 (2.0–2.3)
CCIS = 4 6.4 (8540) 12.0 (1027) 1.8 (1.6–1.9) 2.1 (1.9–2.2)
CCIS from 5 to 7 13.9 (18 643) 10.8 (2022) 1.6 (1.5–1.7) 1.6 (1.5–1.7)
CCIS from 8 to 12 5.9 (7882) 10.7 (841) 1.5 (1.4–1.7) 1.3 (1.2–1.5)
CCIS >12
0.7 (939)
14.6 (137)
2.2 (1.8–2.6)
1.6 (1.3–1.9)

Patients, % (n)
Invasive mechanical ventilation, % (n)
Univariate analysis (95% CI)
Multivariate analysis adjusted on sex, age and CCIS (95% CI)
No obesity 76.1 (102 139) 8.0 (8152) 1 (Ref.) 1 (Ref.)
Obesity (total) 23.9 (32 070) 17.0 (5444) 2.36 (2.27–2.45) 1.88 (1.80–1.95)
Prevalent obesity 67.9 (21 768) 12.4 (2694) 1.63 (1.56–1.71) 1.18 (1.12–1.24)
Incident obesity 32.1 (10 302) 26.7 (2750) 4.20 (4.00–4.41) 3.51 (3.33–3.70)
No diabetes 76.0 (100 200) 8.7 (8902) 1 (Ref.) 1 (Ref.)
Diabetes (total) 24.0 (32 209) 14.6 (4694) 1.78 (1.72–1.85) 1.36 (1.30–1.41)
Prevalent diabetes 71.5 (23 040) 12.2 (2808) 1.45 (1.39–1.52) 1.06 (1.01–1.12)
Incident diabetes 28.5 (9169) 20.6 (1886) 2.71 (2.56–2.86) 1.95 (1.84–2.07)
No hypertension 50.6 (67 596) 7.8 (5263) 1 (Ref.) 1 (Ref.)
Hypertension (total) 49.4 (66 613) 12.5 (8333) 1.69 (1.63–1.76) 1.69 (1.62–1.77)
Prevalent hypertension 73.5 (48 932) 9.9 (4831) 1.30 (1.25–1.35) 1.24 (1.17–1.30)
Incident hypertension 26.5 (17 681) 19.8 (3502) 2.93 (2.79–3.06) 2.48 (2.36–2.61)

Abbreviation: CCIS, Charlson's co-morbidity index score.