Table 1.
Clinical characteristics of adult IPD patients per time period. Data are presented as % (n) or mean (± standard deviation).
| Dec-Feb period |
Mar-May period |
|||||
|---|---|---|---|---|---|---|
| 2014-2019 n=202 | 2019-2020 n=42 | p-value | 2015-2019 n=161 | 2020 n=13 | p-value | |
| 1st wave COVID-19 | ||||||
| Age (years) | 68 ± 15 | 68 ± 14 | 0.97 | 67 ± 15 | 73 ± 14 | 0.20 |
| Gender (female) | 50.0 (101) | 57.1 (24) | 0.50 | 46.0 (74) | 69.2 (9) | 0.15 |
| Nursing home residence | 1.5 (3) | 2.4 (1) | 0.53 | 4.3 (7) | 0 (0) | 1 |
| COPD | 22.8 (46) | 21.4 (9) | 1 | 20.5 (33) | 30.8 (4) | 0.48 |
| Diabetes mellitus type 2 | 21.3 (43) | 14.3 (6) | 0.40 | 16.8 (27) | 15.4 (2) | 1 |
| Cancer | 39.1 (79) | 38.1 (16) | 0.90 | 25.5 (41) | 61.5 (8) | 0.01 |
| Body Mass Index | 25.9 ± 5.4 | 29.2 ± 7.5 | 0.008 | 26.0 ± 4.8 | 24.9 ± 5.7 | 0.43 |
| Confusion as symptom | 16.8 (34) | 16.7 (7) | 1 | 20.5 (33) | 7.7 (1) | 0.47 |
| Oxygen saturation (%) | 93 ± 5 | 93 ± 5 | 0.27 | 93 ± 5 | 93 ± 6 | 0.73 |
| Arterial blood pH | 7.42 ± 0.10 | 7.44 ± 0.07 | 0.31 | 7.42 ± 0.08 | 7.40 ± 0.13 | 0.40 |
| C-reactive protein (mg/dL) | 245 ± 156 | 277 ± 166 | 0.23 | 249 ± 161 | 277 ± 169 | 0.55 |
| Antibiotics use within 48h preceding admission | 4.5 (9) | 4.8 (2) | 1 | 5.6 (9) | 7.7 (1) | 0.55 |
| Pneumonia | 84.7 (171) | 83.3 (35) | 0.82 | 82.0 (132) | 76.9 (10) | 0.71 |
| Empyema | 5.0 (10) | 7.1 (3) | 0.47 | 5.6 (9) | 7.7 (1) | 0.55 |
| Meningitis | 5.4 (11) | 11.9 (5) | 0.16 | 7.5 (12) | 7.7 (1) | 1 |
| Unknown focus | 5.4 (11) | 4.8 (2) | 1 | 6.3 (10) | 7.7 (1) | 0.59 |