Figure 7.

Absence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) viral RNA in coronavirus disease 2019 (COVID‐19)‐associated ischaemic bowels. SARS‐CoV‐2 and angiotensin‐converting enzyme 2 (ACE2) single‐molecule florescence in‐situ hybridisation (smFISH) was performed on lung and ischaemic bowel samples. Top: SARS‐CoV‐2‐positive control smFISH of a human lung sample shows viral RNA localisation to lung macrophages and pneumocytes. Middle and bottom: SARS‐CoV‐2 and ACE2 RNA in‐situ hybridisation of ischaemic bowel cases from two different patients who tested positive for SARS‐CoV‐2. Arrows highlight regions of SARS‐CoV‐2 viral RNA positivity. Dotted lines outline positive ACE2 RNA signals in ischaemic bowel samples. [Colour figure can be viewed at wileyonlinelibrary.com]