Table 2.
Dupilumab effectiveness at Weeks 16 and 32 by sex, baseline body mass index (< 25 and ≥ 25) and baseline Eczema Area and Severity Index (< 30 and ≥ 30).
EASI reduction | All patients (n = 9) | Sex | Baseline BMI | Baseline EASI | |||
---|---|---|---|---|---|---|---|
Male (n = 4) | Female (n = 5) | BMI < 5 (n = 5) | BMI ≥ 25 (n = 4) | EASI < 30 (n = 3) | EASI ≥ 30 (n = 6) | ||
Week 16, n (%) | |||||||
EASI75 | 9 (100) | 4 (100) | 5 (100) | 5 (100) | 4 (100) | 3 (100) | 6 (100) |
EASI90 | 4 (44.4) | 1 (25.0) | 3 (60.0) | 3 (60.0) | 1 (25.0) | 1 (33.3) | 3 (50.0) |
EASI100 | 2 (22.2) | 0 | 2 (40.0) | 1 (20.0) | 0 | 1 (33.3) | 1 (16.7) |
Week 32, n (%) | |||||||
EASI75 | 9 (100) | 4 (100) | 5 (100) | 5 (100) | 4 (100) | 3 (100) | 6 (100) |
EASI90 | 4 (44.4) | 2 (50.0) | 2 (40.0) | 4 (80.0) | 0 | 1 (33.3) | 3 (50.0) |
EASI100 | 2 (22.2) | 0 | 2 (40.0) | 2 (40.0) | 0 | 1 (33.3) | 1 (16.7) |
BMI, body mass index; EASI, Eczema Area and Severity Index.