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. 2021 Jun 30;43(6):1302–1308. doi: 10.1111/ijlh.13640

TABLE 2.

Lymphocyte classification results of 224 COVID‐19 patients on admission

All patients (N = 224) Lymphopenia (N = 110) Nonlymphopenia (N = 114) P value
Total T cells (/μL; 955‐2860) 746.5 (481.0‐1148.0) 505.0 (319.3‐684.3) 1140.0 (895.5‐1481.3) <.001
Decreased 140 (62.5) 99 (90.0) 41 (36.0) <.001
CD8+ T cells (/μL; 320‐1250) 247.0 (152.5‐367.0) 162.0 (85.0‐244.0) 335.5 (247.0‐458.0) <.001
Decreased 147 (65.6) 96 (87.3) 51 (44.7) <.001
CD4+ T cells (/μL; 550‐1440) 420.5 (270.0‐711.0) 291.0 (165.8‐385.8) 680.0 (451.3‐930.5) <.001
Decreased 136 (60.7) 98 (89.1) 38 (33.3) <.001
Natural killer [NK] cells (/μL; 150‐1100) 155.0 (94.0‐244.0) 106.0 (65.0‐199.3) 199.0 (129.0‐277.5) <0.001
Decreased 108 (48.2) 70 (63.6) 38 (33.3) <0.001
Total B cells (/μL; 90‐560) 150.5 (97.8‐264.0) 113.0 (75.0‐152.3) 228.0 (148.3‐341.0) <.001
Decreased 46 (20.5) 37 (33.6) 9 (7.9) <.001
CD4+/CD8+ (0.71‐2.78) 1.7 (1.2‐2.4) 1.5 (1.1‐2.3) 1.9 (1.3‐2.6) .044
Decreased 9 (4.0) 8 (7.3) 1 (0.9) .036
Increased 39 (17.4) 16 (14.5) 23 (20.2) .267

Data are median (IQR), n (%), where N is the total number of patients with available data. P values comparing the confirmed patients and the suspected patients are from χ² test, Fisher's exact test, or Mann‐Whitney U test. Lymphopenia, Patients with lymphopenia on admission. Nonlymphopenia, Patients with nonlymphopenia on admission.