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. 2021 Aug 26;12:710493. doi: 10.3389/fpsyg.2021.710493

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Copyright © 2021 Kalisch, Köber, Binder, Ahrens, Basten, Chmitorz, Choi, Fiebach, Goldbach, Neumann, Kampa, Kollmann, Lieb, Plichta, Reif, Schick, Sebastian, Walter, Wessa, Yuen, Tüscher and Engen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Individual mental health reactivity to stressor exposure (“stressor reactivity”). The regression line shows the normative linear positive relationship between combined exposure to LEs and DHs stressors (E_C,T1−T3) and mental health problems (P_T1−T3) in subjects providing partial data during the first 9 months of the study (monitoring time points T1–T3). The residuals onto the regression line are subjects' deviations from the normative E_C-P relationship. A strong positive deviation reflects high susceptibility of the subject's mental health to the effects of DHs and LEs (high stressor reactivity, SR) during the chosen time window; a strong negative deviation reflects abnormally low susceptibility (low SR). 1–5 denote arbitrarily chosen subjects.