Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 2;8:720955. doi: 10.3389/fmolb.2021.720955

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Ghosh, Bu, Nannenga and Sumner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Schematic representation of integrated analytical workflow (UHPLC-MS-SPE-NMR and MicroED) for automated purification and structure elucidation of targeted metabolites. The platform allows putative identification of metabolites based upon retention time, accurate mass, and MS/MS database searches. Targeted metabolites that are unidentified or require further structural confirmation can be purified simultaneously using the UHPLC-MS-SPE system in an automated manner. Structures of purified metabolites can then be confirmed or elucidated by NMR or MicroED.