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. 2021 Sep 15;41(37):7831–7847. doi: 10.1523/JNEUROSCI.1037-20.2021

Figure 9.

Figure 9.

CP-93129 does not affect ChR2-IPSCs from FSIs. A, Example AP triggered in a FSI (PV-Cre mouse) by a 2-ms light pulse. Optical stimulation resulted in one (black) or two APs (gray). Blue light bar represents LED stimulus. B, Example IPSC amplitude recording and drug treatment for FSI→SPN connections (PV-Cre mouse). Bath application of serotonin receptor 5-HT1B agonist CP-93129 has no effect on IPSCs. C, Average IPSC amplitude change during CP-93129 treatment in PV-Cre mice (N = 4). Horizontal line at 100% was added as visual guideline. Dotted lines represent SEM IPSC amplitude change was normalized against minutes 10–15 (baseline). Each point is an average of six IPSC events. D, Average group synaptic success rate of SPNs with CP-93129. Dotted lines represent SEM. All recordings were done in the presence of KA.