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. Author manuscript; available in PMC: 2021 Sep 16.
Published in final edited form as: Cell Rep. 2021 Sep 7;36(10):109670. doi: 10.1016/j.celrep.2021.109670

Figure 1. lin-28 and lin-46 5′ UTR prevent LIN-46 expression at the L1 and L2 stages.

Figure 1.

(A) The GFP- and mCherry-tagged alleles of lin-28(ma426[lin-28::gfp]) and lin-46(ma398[lin-46::mCherry]). The ma398ma459 allele harbors the “GTAT” deletion (ma459) in the 5′ UTR of lin-46, which is also tagged with mCherry at the C terminus (ma398).

(B) Differential interference contrast (DIC) and fluorescent images showing LIN-28 and LIN-46 expression in wild-type L2- (first row) and L4 (last row)-stage larvae and in lin-28(lf) and lin-46(ma398ma459) L2-stage larvae. Scale bar: 10 μm.

(C) Summary of the LIN-28 and LIN-46 expressions observed during larval stages of wild-type, lin-28(lf), and lin-46(gf/ma398ma459) animals.

See also Figures S1 and S2 and Tables S1 and S2.