Table 1.
Baseline Characteristics at Inclusion by Group
| Global (n=103) | Control (n=51) | Colchicine (n=52) | P value | |
|---|---|---|---|---|
| Age | 51.0±12.0 | 50.3±12.4 | 51.8±11.7 | 0.536 |
| Male sex | 54 (52.4) | 27 (52.9) | 27 (51.9) | 1.000 |
| Prior history | ||||
| Hypertension | 28 (27.2) | 14 (27.5) | 14 (26.9) | 1.000 |
| Dyslipidaemia | 25 (24.3) | 14 (27.5) | 11 (21.2) | 0.606 |
| Diabetes | 15 (14.6) | 9 (17.6) | 6 (11.5) | 0.549 |
| Obesity (BMI > 30 kg/m2) | 22 (21.4) | 9 (17.6) | 13 (25.0) | 0.503 |
| Smoking | 9 (8.7) | 3 (5.9) | 6 (11.5) | 0.505 |
| Cardiovascular disease | 3 (2.9) | 3 (5.9) | 0 (0.0) | 0.234 |
| Cerebrovascular disease | 2 (1.9) | 0 (0.0) | 2 (3.8) | 0.484 |
| Renal insufficiency | 7 (6.8) | 4 (7.8) | 3 (5.8) | 0.979 |
| COPD | 1 (1.0) | 1 (2.0) | 0 (0.0) | 0.992 |
| Obstructive sleep apnoea | 7 (6.8) | 3 (5.9) | 4 (7.7) | 1.000 |
| Characteristics at admission | ||||
| Time from admission (days) | 1.3±0.6 | 1.3±0.6 | 1.2±0.6 | 0.601 |
| Time with symptoms (days) | 7.6±4.4 | 8.3±5.1 | 6.9±3.4 | 0.107 |
| WHO clinical scale | 1.000 | |||
| 3 | 34 (33.0) | 1720 (33.3) | 17 (32.7) | |
| 4 | 69 (67.0) | 34 (66.7) | 35 (67.3) | |
| NEWS scale | 2.5±1.8 | 2.3±1.8 | 2.7±1.9 | 0.272 |
| Systolic blood pressure (mmHg) | 122±17 | 123±15 | 123±19 | 0.918 |
| Diastolic blood pressure (mmHg) | 74.8±11.3 | 73.7±9.8 | 75.9±12.6 | 0.323 |
| Oxygen saturation (%) | 96.3±1.9 | 96.4±1.7 | 96.1±2.2 | 0.537 |
| Temperature (°C) | 36.5±0.6 | 36.6±0.7 | 36.4±0.6 | 0.038 |
| Heart rate (bpm) | 78.1±12.5 | 77.5±12.7 | 78.6±12.3 | 0.655 |
| Breathing rate (rpm) | 17.7±3.7 | 17.5±3.5 | 17.9±4.0 | 0.614 |
| Serum creatinine (mg/dL) | 0.7±0.2 | 0.7±0.2 | 0.8±0.2 | 0.495 |
| GFR e (mL/min/.73m2) | 102±27.9 | 106±31.6 | 98.5±23.6 | 0.162 |
| Lymphocytes (x103/µL) | 1.2±0.5 | 1.2±0.5 | 1.3±0.4 | 0.840 |
| Serum D-dimer (ng/mL) | 332±297 | 318±301 | 345±295 | 0.636 |
| Il-6 (pg/mL) | 35.1±39.1 | 36.7±45.3 | 33.5±32.6 | 0.679 |
| Serum ferritin (ng/mL) | 712±734 | 756±732 | 670±741 | 0.557 |
| AST (U/L) | 39.7±24.5 | 39.4±25.1 | 40.1±24.1 | 0.888 |
| C-reactive protein (mg/dl) | 7.9±6.3 | 8.5±6.3 | 7.3±6.4 | 0.367 |
| Troponin T (pg/mL) | 7.0±11.3 | 8.2±15.6 | 5.9±4.5 | 0.320 |
| NT-proBNP | 139.8±290.1 | 141.1±327.8 | 138.5±253.1 | 0.965 |
Note: Numbers (%) and mean ± standard deviation.
Abbreviations: WHO, world health organization; IL, interleukin; GFR, glomerular filtration rate (MDRD equation); NT-proBNP, N-terminal pro-B-type natriuretic peptide; ALT, alanine aminotransferase; AST, aspartate aminotransferase.