Table 2.
Study End-Points by Group
Global (n=103) | Control (n=51) | Colchicine (n=52) | P value | |
---|---|---|---|---|
WHO scale | ||||
≥1-grade deterioration | 10 (9.7) | 7 (13.7) | 3 (5.8) | 0.303 |
≥ 2-grade deterioration | 2 (1.9) | 2 (3.9) | 0 (0.0) | 0.467 |
Days to 1-grade improvement | 5.36±4.12 | 4.96±4.71 | 5.73±3.49 | 0.350 |
Change at 14 days | −2.29 (1.01) | −2.24 (1.21) | −2.35 (0.76) | 0.579 |
Change at 28 days | −2.48 (0.96) | −2.35 (1.25) | −2.60 (0.53) | 0.199 |
Adverse events | ||||
Death | 2 (1.9) | 2 (3.9) | 0 (0.0) | 0.467 |
ICU admission | 6 (5.8) | 4 (7.8) | 2 (3.8) | 0.656 |
Days in ICU | 7.17±6.49 | 8.25±8.10 | 5.00±0.00 | 0.621 |
Advanced respiratory support | 6 (5.8) | 4 (7.8) | 2 (3.8) | 0.656 |
High outflow oxygen | 2 (1.9) | 1 (2.0) | 1 (1.9) | |
Non-invasive ventilation | 2 (1.9) | 1 (2.0) | 1 (1.9) | |
Invasive ventilation | 2 (1.9) | 2 (3.9) | 0 (0.0) | |
Length of hospitalization | 6.18±4.40 | 5.76±4.89 | 6.60±3.86 | 0.340 |
Abbreviation: ICU, intensive care unit.