Table 2:
Association between postinduction MRI features, the Dworak score and DFS in univariate analysis
| N=128 | Values | DWORAK (117) | DFS (n=128) | |||||
|---|---|---|---|---|---|---|---|---|
| 0–1–2 | 3–4 | P-value | HR | 95%CI | P-value | |||
|
| ||||||||
| Tumor Volume | 12 [0–217] | 16.5 [0–217] | 9.3 [0–47.6] | <0.001 | 1.01 | 1.00–1.02 | 0.019 | |
|
| ||||||||
| Volume regression | ≤60 | 51 (39.84%) | 20 (47%) | 23 (53%) | 3.15 | 1.51–6.59 | ||
|
| ||||||||
| >60 | 77 (60.16%) | 36 (51%) | 35 (49%) | 0.66 | 1 | 0.002 | ||
|
| ||||||||
| T | 0/1/2 | 39 (29.32%) | 11 (30%) | 26 (70%) | 1 | |||
|
| ||||||||
| 3/4 | 94 (70.68%) | 45 (56%) | 35 (44%) | 0.008 | 2.18 | 0.84–5.67 | 0.083 | |
|
| ||||||||
| CRM | 0 | 91 (70.0%) | 37 (45%) | 45 (55%) | 0.17 | 1 | 0.037 | |
|
| ||||||||
| 1 | 39 (30.0%) | 19 (59%) | 13 (41%) | 2.16 | 1.07–4.39 | |||
|
| ||||||||
|
| ||||||||
| N | 0 | 53 (39.85%) | 19 (39%) | 30 (61%) | 1 | |||
|
| ||||||||
| 1 | 80 (60.15%) | 37 (54%) | 31 (46%) | 0.095 | 2.0 | 0.89–4.46 | 0.077 | |
|
| ||||||||
| Sphincter involvement | 0 | 126 (95.45%) | 53 (48%) | 58 (52%) | 1 | |||
|
| ||||||||
| 1 | 6 (4.55%) | 3 (60%) | 2 (40%) | 0.67 | 1.65 | 0.39–6.93 | 0.522 | |
|
| ||||||||
| Tumor Location | Low | 44 (33.08%) | 12 (30%) | 28 (70%) | 1 | |||
|
| ||||||||
| Mid | 68 (51.13%) | 32 (53%) | 28 (47%) | 0.85 | 0.38–1.89 | |||
|
| ||||||||
| High | 21 (15.79%) | 12 (71%) | 5 (29%) | 0.009 | 1.06 | 0.39–2.92 | 0.866 | |
|
| ||||||||
| EMVI | 0 | 89 (66.92%) | 29 (37%) | 50 (63%) | 1 | |||
|
| ||||||||
| 1 | 44 (33.08%) | 27 (71%) | 11 (29%) | <0.001 | 2.25 | 1.11–4.55 | 0.0255 | |
|
| ||||||||
| Mucinous Content | 0 | 95 (71.97%) | 39 (46%) | 46 (54%) | 1 | |||
|
| ||||||||
| 1 | 37 (28.03%) | 17 (55%) | 14 (45.2%) | 0.39 | 1.92 | 0.94–3.94 | 0.080 | |
|
| ||||||||
| TRG | 1 | 1 (0.75%) | 0 | 1 (100%) | ||||
|
| ||||||||
| 2 | 41 (30.83%) | 10 (26%) | 29 (74%) | |||||
|
| ||||||||
| 3 | 31 (23.31%) | 7 (28%) | 18 (72%) | |||||
|
| ||||||||
| 4 | 51 (38.35%) | 31 (70%) | 13 (30%) | |||||
|
| ||||||||
| 5 | 9 (6.77%) | 8 (100%) | 0 | <0.001 | ||||
|
| ||||||||
| TRG 1–2/3–5 | 1–2 | 42 (31.58%) | 10 (25%) | 30 (75%) | 1 | |||
|
| ||||||||
| 3–4–5 | 91 (68.42%) | 46 (60%) | 31 (40%) | <0.001 | 2.73 | 1.05–7.11 | 0.0227 | |