Table 3:
Association between presurgery MRI features, the Dworak score and DFS in univariate analysis.
N=94 | Values | DWORAK (n=81) | DFS (n=94) | |||||
---|---|---|---|---|---|---|---|---|
| ||||||||
0–1–2 | 3–4 | P-value | HR | 95% CI | P-value | |||
| ||||||||
Tumor Volume | 6 [0–111] | 8.5 [0–111] | 0 [0–37] | <0.001 | 1.01 | 0.99–1.03 | 0.29 | |
| ||||||||
Volume regression | ≤60 | 20 (21.28%) | 9 (60%) | 6 (40%) | 2.17 | 0.80–5.88 | ||
| ||||||||
>60 | 74 (78.72%) | 21 (32%) | 45 (68%) | 0.041 | 1 | 0.14 | ||
| ||||||||
T | 0/1/2 | 49 (52.13%) | 10 (22%) | 35 (78%) | 1 | |||
| ||||||||
3/4 | 45 (47.87%) | 20 (56%) | 16 (44%) | 0.003 | 1.98 | 0.73–5.36 | 0.17 | |
| ||||||||
CRM | 0 | 71 (82.56%) | 24 (39%) | 38 (61%) | 0.618 | 1 | 0.21 | |
| ||||||||
1 | 15 (17.44%) | 6 (46%) | 7 (54%) | 2.04 | 0.70–5.91 | |||
| ||||||||
| ||||||||
N | 0 | 62 (65.96%) | 18 (31%) | 40 (69%) | 1 | |||
| ||||||||
1 | 32 (34.04%) | 12 (52%) | 11 (48%) | 0.076 | 1.79 | 0.69–4.63 | 0.24 | |
| ||||||||
Sphincter involvement | 0 | 93 (98.94%) | NA | NA | NA | NA | NA | NA |
| ||||||||
1 | 1 (1.06%) | |||||||
| ||||||||
Tumor Location | Low | 35 (38.04%) | 8 (25%) | 24 (75%) | 1 | |||
| ||||||||
Mid | 44 (47.83%) | 15 (41%) | 22 (59%) | 0.59 | 0.20–1.75 | |||
| ||||||||
High | 13 (14.13%) | 7 (70%) | 3 (30%) | 0.037 | 1.38 | 0.40–4.71 | 0.39 | |
| ||||||||
EMVI | 0 | 78 (82.98%) | 22 (32%) | 47 (68%) | 1 | |||
| ||||||||
1 | 16 (17.02%) | 8 (67%) | 4 (33%) | 0.048 | 3.11 | 1.15–8.43 | 0.0384 | |
| ||||||||
Mucinous Content | 0 | 73 (78.49%) | 21 (33%) | 42 (67%) | 1 | |||
| ||||||||
1 | 20 (21.51%) | 8 (47%) | 9 (53%) | 0.296 | 1.46 | 0.51–4.16 | 0.49 | |
| ||||||||
TRG | 1 | 21 (22.34%) | 1 (5%) | 18 (95%) | ||||
| ||||||||
2 | 28 (29.79%) | 5 (19%) | 21 (81%) | |||||
| ||||||||
3 | 23 (24.47%) | 9 (56%) | 7 (44%) | |||||
| ||||||||
4 | 19 (20.21%) | 13 (72%) | 5 (28%) | |||||
| ||||||||
5 | 3 (3.19%) | 2 (100%) | 0 | <0.001 | ||||
| ||||||||
TRG 1–2/3–5 | 1–2 | 49 (52.13%) | 6 (13%) | 39 (87%) | 1 | |||
| ||||||||
3–4–5 | 45 (47.87%) | 24 (67%) | 12 (33%) | <0.001 | 4.30 | 1.40–13.21 | 0.005 |