Table 1.
Baseline characteristics
| Characteristic | Total (n = 20*) | Treatment | |
|---|---|---|---|
| Peanut (n=15) | Placebo (n=5) | ||
| Age at baseline (years), median (IQR) | 26.5 (23.5, 33.5) | 26 (23, 31) | 31 (24, 47) |
| Males, n (%) | 15 (75%) | 11 (73%) | 4 (90%) |
| White, n (%) | 12 (60%) | 8 (53%) | 4 (80%) |
| Atopic conditions, n (%) | |||
| Asthma | 16 (80%) | 12 (80%) | 4 (80%) |
| Allergic rhinitis | 17 (85%) | 12 (80%) | 5 (100%) |
| Atopic dermatitis | 11 (55%) | 8 (53%) | 3 (60%) |
| Other food allergies | 11 (55%) | 6 (40%) | 5 (100%) |
| Total serum IgE (kU/L), median (IQR) | 253.0 (88.5, 461.3) | 201.0 (88.0, 398.5) | 335.0 (242.0, 458.0) |
| Peanut-specific IgE (kU/L), median (IQR) | 6.6 (2.5, 70.8) | 6.3 (2.1, 57.5) | 26.1 (3.1, 163.0) |
| Peanut-specific IgG4 (ng/L), median (IQR) | 0.3 (0.1, 0.4) | 0.2 (0.1, 0.4) | 0.3 (0.2, 0.3) |
| Peanut skin prick test wheal diameter (mm), median (IQR) | 13.5 (7.8, 17.8) | 16.0 (8.6, 19.9) | 9.0 (7.0, 11.5) |
| Absolute eosinophil counts (cells/L), median (IQR) | 0.2 (0.1, 0.3) | 0.2 (0.1, 0.3) | 0.1 (0.1, 0.3) |
IQR = interquartile range.
*
Excluded 1 participant who was not randomized into the POISED parent study.