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. 2021 Sep 2;12:702769. doi: 10.3389/fphys.2021.702769

TABLE 3.

Associations of social jetlag with delta difference of metabolic parameters and BP over 1-year follow-up (n = 625).

All (n = 625)
Type 2 diabetes (n = 178)
SOD (n = 447)
β p β p β P
Fasting glucose, mg/dL 0.11(0.2−2.4) 0.02a† 0.30(2.5−9.2) < 0.001b −0.06(−1.2−0.3) 0.27
HbA1c,% −0.02(−0.2−0.2) 0.80 −0.02(−0.3−0.3) 0.85 −0.02(−0.2−0.2) 0.86
Total cholesterol, mg/dL −0.03(−0.9−4.6) 0.53 −0.08(−1.5−1.4) 0.93 −0.04(−1.0−0.5) 0.52
HDL-c, mg/dL −0.08(−0.1−0.2) 0.10 −0.02(0.4−0.3) 0.80 −0.11(−1.0−0.02) 0.06
LDL-c, mg/dL −0.07(−2.6−0.4) 0.15 −0.08(−3.8−1.5) 0.39 −0.06(−2.8−0.85) 0.62
Triglycerides, mg/dL 0.09(0.1−5.9) 0.04c 0.22(1.6−14.4) 0.01d 0.03(−2.3−4.3) 0.56
Systolic BP, mm Hg −0.01(−0.2−0.2) 0.74 −0.09(−3.3−0.9) 0.83 −0.09(−1.8−0.1) 0.10
Diastolic BP, mm Hg −0.06(−0.07−0.2) 0.27 −0.14(−2.6−0.1) 0.08 −0.03(−1.0−0.5) 0.47

Variables correlated on Pearson or Spearman correlation (r > 0.20) were subjected to stepwise multivariate linear regression. aMultivariate linear regression analysis adjusted for age, sex, BMI, menopause status, time since diagnosis of type 2 diabetes, use of sleeping pills and total calories consumed after 9:00 p.m. bMultivariate linear regression analysis adjusted for age, sex, BMI, time since diagnosis of type 2 diabetes, menopause status and total calories consumed after 9:00 p.m. cMultivariate linear regression analysis adjusted for age, sex, time since diagnosis of dyslipidemia, and total calories consumed after 9:00 p.m. dMultivariate linear regression analysis adjusted for age, sex, BMI, time since diagnosis of dyslipidemia, menopause status and minutes of physical activity per week. r2 adjusted = 0.04. r2 adjusted = 0.07. r2 adjusted = 0.02. SOD, systemic arterial hypertension and/or obesity and/or dyslipidemia group; HbA1c, glycated hemoglobin.