Supplementary Table 3.

Cox proportional hazards regression model showing the effect of four variables on risk of discharge from hospital

Characteristics	Coefficient	SE	Wald χ2	P	HR	95% CI
Aggressive diuresis	0.11	0.21	0.27	0.60	1.12	0.74-1.68
LVEF	0.007	0.005	2.19	0.14	1.01	1.00-1.017
Furosemide	<0.001	0.003	0.001	0.98	1.000	0.995-1.005
Cr >1.6	−0.10	0.33	0.10	0.75	0.90	0.47-1.72
Cr >1.6 X	0.001	0.004	0.07	0.79	1.001	0.99-1.01

Aggressive diuresis, indicates ≥2400 mL/24 h urine, Furosemide, Total 24 h dose of furosemide used in 24 h; Cr >1.6, indicates >1.6 mg/dL serum creatinine at time of admission equivalent to stage 3 or less kidney disease; Cr >1.6 X furosemide, indicates interaction between furosemide and creatinine >1.6 mg/dL. LVEF: Left ventricular ejection fraction, HR: Hazard ratio, SE: Standard error, CI: Confidence interval, Cr: Creatinine