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. 2021 Sep 2;12:666449. doi: 10.3389/fphys.2021.666449

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Copyright © 2021 Cai, Wen, Ma, Mai, Zhan, Wang, Zhang, Chen, Li, Wu, Li and Luo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Huang-Lian-Jie-Du decoction inhibited ox-LDL-induced RAW264.7 cells lipid accumulation. (A) Cytotoxicity of HLJDD on RAW264.7 cells. Values are expressed as the mean±SD from three independent experiments (^**p<0.01 vs. with control group). (B) Representative images of Oil Red O staining in vitro RAW264.7 cells. Scale bar=20μm. (C) Percent positive foam cells were measured by Image J software. Values are expressed as the mean±SD from three independent experiments (^**p<0.01 vs. ox-LDL-treated group; one-way ANOVA). ox-LDL, oxidized low-density lipoprotein.