Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Irg1 is dispensable for macrophage control of Brucella infection. (A to F) Macrophages from WT and IRG1−/− mice (n = 3 wells/group) were infected with B. melitensis 16M at an MOI of 20 or 100. At various time points after infection, intracellular CFU levels were determined (A and B), and IL-1β (C and D) and CXCL2 (E and F) were measured in supernatants. Error bars depict SD from the means. Data are representative of 3 independent experiments. *, P < 0.05 compared to WT macrophages.
