Genetic differences between clinical isolates of S. aureus. (A) Multilocus sequence typing (MLST) of the clinical isolates (TI1, TI2, and TI3) and the reference strains NRS384 (USA300), FPR3757 (USA300), and N315 (USA100) listed with the allele identifiers (* denotes the closest match [no exact allele identification]) for each MLST locus, clonal complex (CC), and strain type (ST). (B to E) Enumerated single nucleotide polymorphisms (SNPs) compared to the reference strain (B), total number of genes with at least one SNP (C), and percentage of adhesin genes (D) or immune evasion genes (E), as designated in Fig. S8 in the supplemental material, with at least one SNP.