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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Laser Photon Rev. 2021 Jun 27;15(8):2100072. doi: 10.1002/lpor.202100072

Figure 1. Architecture of GEOMScope.

Figure 1.

(a) Experimental PSF measurement from single point source. Scale bar: 2 mm; inset, 200 μm. (b) Schematic of GEOMScope. Raw image is simulated through ray tracing in OpticStudio. MLA, microlens array. (c) Initial reconstruction at different depths through pixel back projection. (d) Resolved objects with background suppression through a trained neural network. (e) Comparison between GEOMScope and other lensless imagers (FlatScope [11], DiffuserCam [10], 3D Miniscope [14], MLA Mesoscope [16]) on the number of camera pixel and object voxel pair versus computation time (with the processor type and required RAM) in reconstruction. The number of object voxel is either the reported value or the derived value as the ratio of imaged volume and 3D resolution.