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. 2021 Sep 2;3(3):fcab205. doi: 10.1093/braincomms/fcab205

Table 2.

Baseline performance on cognition and language in nfvPPA, lvPPA and healthy controls

nfvPPA lvPPA HC F P Post-hoc
(n = 39) (n = 40) (n = 40)
ACE Total 74.2 ± 14.7 59.4 ± 16.8 95.5 ± 3.6 77.466 <0.001

  • Patients < HC

  • lvPPA < nfvPPA
 Attention 15.7 ± 2.7 12.9 ± 3.8 17.5 ± 1.0 28.639 <0.001

  • Patients < HC

  • lvPPA < nfvPPA
 Memory 19.9 ± 5.9 12.5 ± 6.4 24.5 ± 1.8 56.426 <0.001

  • Patients < HC

  • lvPPA < nfvPPA
 Fluency 5.4 ± 3.0 4.5 ± 2.8 12.6 ± 1.2 130.76 <0.001 Patients < HC
 Language 19.2 ± 4.2 16.9 ± 5.5 25.4 ± 1.1 46.967 <0.001

  • Patients < HC

  • lvPPA < nfvPPA
 Visuospatial 14.1 ± 2.2 12.6 ± 3.2 15.6 ± 0.7 17.044 <0.001

  • Patients < HC

  • lvPPA < nfvPPA
SYDBAT
 Naming 20.3 ± 6.0 14.9 ± 6.8 27.4 ± 2.0 53.669 <0.001

  • Patients < HC

  • lvPPA < nfvPPA
 Semantic 25.2 ± 4.0 24.1 ± 5.2 28.8 ± 1.1 15.435 <0.001 Patients < HC
 Comprehension 27.5 ± 2.6 26.0 ± 3.0 29.5 ± 1.0 20.978 <0.001

  • Patients < HC

  • lvPPA < nfvPPA
 Repetition 21.6 ± 8.7 25.5 ± 5.5 29.8 ± 0.5 18.941 <0.001

  • Patients < HC

  • nfvPPA < lvPPA

Values are mean ± standard deviation. ACE, Addenbrooke’s Cognitive Examination; lvPPA, logopenic variant primary progressive aphasia; nfvPPA, non-fluent variant primary progressive aphasia; SYDBAT, Sydney Language Battery. Missing data: SYDBAT Total missing for 2 lvPPA, 2 Controls; SYDBAT Naming missing for 1 lvPPA; SYDBAT Semantic missing for 1 lvPPA, 2 controls; SYDBAT Comprehension missing for 1 lvPPA.