Table 2. Distribution of tumor types in all LFS PV-positive patients (n = 26).

Tumor types diagnosed in PV carriers	Number of tumors per PV group (A/B)	OR (95% CI), p value	Number of patients per group (A/B)	% PV carriers per group (A/B)	Age at diagnosis (range when >1) in each group (A/B)
Adrenocortical Carcinoma	1 / 13	16.0 (1.5–875.8), 0.009	1 / 13	12.5 / 72.2	44 / 0 to 17
Breast	8 / 4	0.18 (0.03–1.0), 0.03	5 / 3	62.5 / 16.6	21 to 38 / 23 to 57
CNS	2 / 2	0.39 (0.02–6.53), 0.56	2/ 2	25 / 11.1	5 to 11 / 1
Osteosarcoma	3 / NA	-	2 / NA	25 / NI	12 to 38 / NA
Thyroid	1 / NA	-	1 / NA	12.5 / NI	37 / NA

DBD, pathogenic variants located in the DNA-binding domain; CNS, Central Nervous System tumors; NA, not applicable; NI, not identified.