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. 2021 Sep 16;17(9):e1009804. doi: 10.1371/journal.ppat.1009804

Fig 3. Mortality in critically ill COVID-19 patients is associated with perturbations in serum protein levels.

Fig 3

(A) Fold-change in median serum protein concentration between critically ill COVID-19 patients who died versus survived. (B-C) Kaplan-Meier survival curves of critically ill COVID-19 patients based on concentration of the indicated analyte. Only proteins where FDR<0.1 (from (A)) are plotted. (B) Kaplan-Meier survival curves for serum proteins where above median expression is associated with increased mortality. (C) Kaplan-Meier survival curves for serum proteins where above median expression is associated with decreased mortality. (D) Median serum cytokine concentration in critically ill COVID-19 patients and critically ill influenza patients. (A) Mann-Whitney U-test with Benjamini-Hochberg FDR calculation on data presented in S4A Fig.